Linerase Collagen (HTIC) – Professional Dermal Bio-Stimulator for Advanced Skin Regeneration

Linerase Collagen represents a pinnacle in regenerative aesthetic medicine, engineered to fundamentally rejuvenate skin at the cellular level. This innovative injectable treatment utilizes 100 mg of highly purified Heterologous Type I Collagen (HTIC) powder to stimulate the body’s natural regenerative processes. Developed by Professor Andrea Corbo and his scientific team, Linerase is not a filler but a potent bio-stimulator that activates fibroblasts, inducing the production of new Type III collagen—the cornerstone of youthful, firm, and elastic skin.

The mechanism is a sophisticated five-stage process: upon injection, the HTIC is hydrolyzed into bioactive tripeptides (like Pro-Hyp-Gly) and amino acids. These tripeptides act as powerful bio-signals, awakening dormant fibroblasts and mimicking the effect of dermal growth factors. The newly activated fibroblasts then use the available amino acids to synthesize fresh Type III collagen, while the bioactive peptides concurrently inhibit the enzymes (MMPs) responsible for collagen breakdown, ensuring a durable and lasting regenerative outcome. This product is non-allergenic, as the resulting tripeptides have a molecular weight far below the 10kDa threshold required to trigger an allergic response.

Key Features & Benefits:

• Advanced Dermal Bio-Stimulation: Actively stimulates fibroblasts to produce new, healthy Type III collagen, fundamentally improving skin structure.

• Comprehensive Anti-Aging: Effectively improves skin elasticity, dermal thickness, and hydration while reducing the appearance of fine lines and wrinkles.

• Versatile Treatment Areas: Ideal for rejuvenating the face, neck, décolleté, and hands.

• Scar & Stretch Mark Repair: Significantly enhances the remodeling of the extracellular matrix, improving the appearance of post-surgical scars, acne scars, and striae.

• Wide Range of Medical Indications: Proven effective for intimate area rejuvenation, rheumatology and joint support, and periodontal and gum regeneration.

• Proactive “Prejuvenation”: An excellent preventative treatment for younger patients (ages 20-35) to preserve the extracellular matrix and delay the onset of visible aging.

• High Safety Profile: Certified as a Class III Medical Device (CE 0477), manufactured under ISO 13485 standards, and proven to be non-allergenic with no adverse reactions reported.

• Clinically Proven Efficacy: Effects begin to show after 72 hours, with peak results visible at 2 weeks.

   

Treatment Protocol:

• Attack Phase: 1 session every 2 weeks, for a total of 4 sessions.

• Maintenance Phase: 1 session every 2 months to maintain results.

How to Use (For Professionals Only):

• Preparation: Reconstitute the 100 mg collagen powder with 5 ml of solution (typically 4.5 ml of saline and 0.5 ml of anesthetic like lidocaine). The solution must be prepared immediately before use.

• Injection Technique: Administer via intradermal injections using a 30G or 32G (4mm) needle. Inject 0.1 ml per point, maintaining a 2 cm distance between injection sites. For delicate areas, reduce volume to 0.05 ml per point with closer spacing.

• Post-Treatment: Apply the Linerase Restoring Mask for 10-15 minutes to calm the skin and reduce any redness.

   

Package Contents:

• One glass vial containing 100 mg of sterile Heterologous Type I Collagen powder of equine origin.